Table 2.

Effects of azilsartan, perindopril and combined groups on the hippocampal level of Aβ-42 in AlCl₃ -induced Alzheimer’s disease in rats.

Groups	Aβ-42 (pg/mg of protein)
Negative Control	74 ± 2.04*
Vehicle	70.58 ± 1.21*
AlCl3 (100 mg/kg) - Positive control	118 ± 5.01
Azilsartan 1 (3.5 mg/kg)	70 ± 2.30*
Azilsartan 2 (7 mg/kg)	72 ± 1.12*
Perindopril 1 (0.5 mg/kg)	70 ± 3.10*
Perindopril 2 (1 mg/kg)	68 ± 2.33*
Combined 1 (Azilsartan 1 + Perindopril 1)	66.40 ± 1.17*
Combined 2 (Azilsartan 2 + Perindopril 2)	63 ± 1.94*

Values are expressed as means ± SEM, n = 6 rats.

^*P < 0.001 compared with the corresponding AlCl₃ group values; by one way ANOVA and Tukey HSD post hoc test.