Fig. 4.

Etanercept reduced NF-κBp65 expressing CD4 + and CD8 + T cells peripherally in db/db mice. A and B. The effects of ETN on NF-κBp65⁺ and NF-κBp65⁺-expressing CD4⁺ and CD8⁺ T cells in the peripheral blood (analyzed using flow cytometry). C. Representative dot plots for one mouse from each group using flow-cytometric studies. *P < 0.05 compared with db/db saline-treated mice. Data are shown as mean ± SEM (n = 4).