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. 2020 May 16;9(1):36–48. doi: 10.1302/2046-3758.91.BJR-2019-0055.R2

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© 2020 Author(s) et al

Open Access This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credted. See https://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 6. — Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways associated with protein-protein interactions of genes dysregulated by physical exercise. The set of genes present in the first three clusters for upregulated and downregulated genes were analyzed in the STRING database that showed the associated KEGG signalling pathways. The signalling pathways of relevance in arthritis were selected and marked with different colours. Line thickness indicates the strength of data support. CG, count in gene set; FDR, false discovery rate.