Table 3.
Quantitative functional observational battery pretreatment observations of males. Mean + SD are given. * indicates significance (P = 0.05).
| Group 1, control | Group 2, 100 mg/kg/day UA | Group 3, 300 mg/kg/day UA | Group 4. 1000 mg/kg/day UA | |
|---|---|---|---|---|
| Arena rearing | 11.5 ± 2.5 | 9.9 ± 3.8 | 10.3 ± 3.4 | 8.2 ± 4.6 |
| Forelimb Grip strength mean (g) | 165.00 ± 26.50 | 167.40 ± 38.49 | 159.43 ± 37.66 | 172.46 ± 52.94 |
| Handlimb Grip strength mean (g) | 130.25 ± 19.55 | 132.14 ± 28.91 | 137.30 ± 19.91 | 130.09 ± 38.53 |
| Handlimb splay mean (cm) | 6.94 ± 0.46 | 8.18 ± 1.54 | 7.50 ± 1.66 | 7.40 ± 1.15 |
| Body temp (Celsius) | 37.40 ± 0.46 | 37.51 ± 0.43 | 37.41 ± 0.43 | 37.26 ± 0.25 |
| Tail flick (sec) | 2.170 ± 0.846 | 2.370 ± 0.469 | 2.110 ± 0.247 | 2.440 ± 0.369 |