Table 11.

Summary of the gross pathology findings; effect of UA on the lung, lymph node, muscle, nerves, ovary, oviduct and pancreas. N.V.L = no visible lesions. Lesions were found on/in the lung in both the test groups and the control group in both sexes.

		Male				Female
		Group 1, Control	Group 2, 100 mg/kg/day	Group 3, 300 mg/kg/day	Group 4, 1000 mg/kg/day	Group 1, Control	Group 2, 100 mg/kg/day	Group 3, 300 mg/kg/day	Group 4, 1000 mg/kg/day
	Number of animals	10	10	10	10	10	10	10	10
Lung	Submitted	10	10	10	10	10	10	10	10
	N.V.L	4	5	5	5	7	9	9	9
	Focus	0	0	1	0	0	0	0	0
	Focus; dark	1	3	1	2	0	0	0	1
	Focus; pale	0	0	0	1	1	1	0	0
	Discoloration; mottled	4	3	3	2	2	0	1	0
Lymph node, mesenteric	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	10	10	10	10	10	10	10
Muscle, skeletal	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	10	10	10	10	10	10	10
	Infiltration, mononuclear cell, minimal	10	10	10	10	10	10	10	10
Nerve, optic	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	10	10	10	10	10	10	10
	Not examined, not present	10	10	10	10	10	10	10	10
Nerve, sciatic	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	10	10	10	10	10	10	10
Ovary	Examined	–	–	–	–	10	10	10	10
	N.V.L	–	–	–	–	10	10	10	10
Oviduct	Submitted	–	–	–	–	10	10	10	10
	N.V.L	–	–	–	–	10	10	10	10
Pancreas	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	10	10	10	10	10	10	10