Table 13.

Summary of the gross pathology findings; effect of UA on the tongue, trachea, ureter, urinary bladder, uterus and vagina. N.V.L = no visible lesions. Calculus was found in the urinary bladder in two animals, one in the low dose group and one in the medium dose group in males.

		Male				Female
		Group 1, Control	Group 2, 100 mg/kg/day	Group 3, 300 mg/kg/day	Group 4, 1000 mg/kg/day	Group 1, Control	Group 2, 100 mg/kg/day	Group 3, 300 mg/kg/day	Group 4, 1000 mg/kg/day
	Number of animals	10	10	10	10	10	10	10	10
Tongue	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	10	10	10	10	10	10	10
Trachea	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	10	10	10	10	10	10	10
Ureter	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	10	10	10	10	10	10	10
Urinary bladder	Submitted	10	10	10	10	10	10	10	10
	N.V.L	10	9	9	10	10	10	10	10
	Calculus	0	1	1	0	0	0	0	0
Uterus	Examined	–	–	–	–	10	10	10	10
	N.V.L	–	–	–	–	10	10	10	10
Vagina	Submitted	–	–	–	–	10	10	10	10
	N.V.L	–	–	–	–	10	10	10	10