Figure 1.

Study design.

^{LBBB, Left Bundle Branch Block; MACE, major adverse cardiovascular events defined as composite of all-cause mortality, stroke, recurrent MI, and repeat unplanned revascularization; NACMI, North American COVID-19 ST-Segment Elevation Myocardial Infarction; PUI, Persons Under Investigation; STEMI, ST-segment-elevation myocardial infarction.}

*Confirmed includes those known to be positive for COVID 19 and PUI subsequently confirmed for COVID 19;

** Groups of interest will include patients developing in-hospital STEMI, those not taken to the cardiac catheterization laboratory, those without a clear culprit artery and those receiving fibrinolytic therapy.