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Effect of MDESm on cotton pellet-induced granuloma in rats.
| Treatment | Dose (mg/kg) | Mean weight (mg) | % reduction |
|---|---|---|---|
| Control (dist. water) | 2 (ml/kg) | 0.28 ± 0.02 | — |
| Ibuprofen | 100 | 0.19 ± 0.032∗ | 32.14 |
| MDESm | 100 | 0.17 ± 0.016∗ | 39.28 |
| MDESm | 200 | 0.23 ± 0.029 | 17.85 |
| MDESm | 400 | 0.23 ± 0.012 | 17.85 |
Mean ± SEM, n = 5; ∗p < 0.05 compared to control (one-way ANOVA; Dunnett's post hoc tests). MDESm = methanol-dichloromethane extract of Stemonocoleus micranthus.
