Table 7.
Effect of MDESm on haematological parameters in mice.
| Treatment | Dose (mg/kg) | WBC (cells/μL) | Hb (g/dL) | Platelets (cells/μL) | Neutrophil (cells/μL) | Lymphocytes (cells/μL) |
|---|---|---|---|---|---|---|
| Control (dist. water) | — | 9120 ± 1563 | 13.38 ± 0.31 | 222000 ± 48104 | 22.4 ± 3.74 | 77.6 ± 3.74 |
| Levamisole | 50 | 15880 ± 3172∗ | 13.46 ± 0.44 | 388000 ± 77549 | 21.0 ± 3.79 | 79.0 ± 3.79 |
| MDESm | 100 | 10575 ± 1003 | 11.90 ± 0.40 | 255000 ± 71821 | 18.7 ± 3.42 | 81.3 ± 3.42 |
| MDESm | 200 | 7980 ± 1285 | 13.90 ± 0.85 | 200000 ± 35777 | 23.6 ± 3.50 | 76.8 ± 3.73 |
| MDESm | 400 | 9925 ± 726 | 13.49 ± 0.68 | 217500 ± 51700 | 22.2 ± 3.81 | 77.5 ± 3.81 |
Mean ± SEM, n = 5; ∗p < 0.05 compared to control (one-way ANOVA; Dunnett's post hoc test). MDESm = methanol-dichloromethane extract of Stemonocoleus micranthus.