Table 1.

Demographics for the PD and CTL groups

	PD (n = 154)	CTL (n = 62)	p-value
Age (years)	61.6 ± 8.9 (40–82)	61.5 ± 10 (40–81)	0.87 §
Male distribution	61.7% (98/154)	61.5% (41/62)	0.73 #
Right-handedness	90.3% (139/154)	82.3% (51/62)	0.19 #
Disease duration (months)	25.5 ± 17.8 (2–77)	NA	–
MDS-UPDRS III at baseline	22.3 ± 9.7 (5–46)	0.5 ± 1.2 (0–8)	< 0.0001 §
MDS-UPDRS III axial subscore	4.0 ± 2.6 (0–12)	0.1 ± 0.3 (0–2)	< 0.0001 §
MDS-UPDRS III right-sided items subscore	7.9 ± 4.8 (0–20)	0.2 ± 0.5 (0–3)	< 0.0001 §
MDS-UPDRS III left-sided items subscore	7.7 ± 6.1 (0–23)	0.3 ± 0.6 (0–3)	< 0.0001 §
Hoehn-Yahr scale	1.5 ± 0.5 (1–2)	0 (0–0)	< 0.001 #
MOCA	27.4 ± 2.2 (20–30)	28.2 ± 1.2 (26–30)	0.19 §
GDS	5.3 ± 1.4 (1–11)	5.1 ± 1.2 (3–10)	0.39 §
SCOPA-AUT	10.5 ± 6.0 (0–40)	7.5 ± 4.5 (0–19)	0.0002 §
SCOPA-AUT Gastrointestinal subscore	2.3 ± 1.9 (0–11)	0.8 ± 1.0 (0–4)	<  0.0001 §
SCOPA-AUT Urological subscore	3.9 ± 2.5 (0–14)	3.2 ± 2.3 (0–12)	0.03 §
Epworth Sleepiness Scale	6.2 ± 4.0 (0–19)	5.9 ± 3.3 (0–15)	0.68 §
REM-sleep behavior disorder screening questionnaire	4.3 ± 2.6 (1–12)	2.9 ± 2.2 (0–10)	<  0.001 §

Baseline demographics of PD and CTL subjects included in the study. Statistical tests: Chi-square #, Mann-Whitney U test §. NA not applicable