. 2020 May 15;12:59. doi: 10.1186/s13195-020-00627-0

Table 2.

Dysregulated miRNAs between amyloid-positive AD and amyloid-negative cognitively normal controls

MiRNA	Log₂ FC (AD vs controls)	Fold change^a	p value (unadj)	p value (FDR-corrected)
hsa-miR-218-1-5p	2.84	7.15	5.32E-08	4.34E-05
hsa-miR-4482-3p	− 1.54	0.34	8.79E-05	0.035865
hsa-miR-16-2-3p	0.78	1.72	0.000409	0.095074
hsa-miR-4669-3p	1.30	2.45	0.000466	0.095074
hsa-let-7b-5p	0.75	1.69	0.000771	0.125787
hsa-miR-320a-3p	0.56	1.47	0.001074	0.132259
hsa-miR-574-5p	0.78	1.71	0.001135	0.132259
hsa-miR-5010-5p	0.72	1.65	0.001754	0.178899
hsa-miR-181a-1-5p	0.46	1.38	0.004002	0.277468
hsa-miR-1306-3p	0.68	1.60	0.004171	0.277468
hsa-miR-320c-1-3p	0.53	1.45	0.004248	0.277468
hsa-miR-3682-3p	0.68	1.60	0.004318	0.277468
hsa-miR-7113-5p	0.67	1.59	0.004566	0.277468
hsa-miR-30a-5p	0.67	1.59	0.00476	0.277468
hsa-miR-6793-3p	0.50	1.41	0.005823	0.316788
hsa-miR-3135a-5p	0.60	1.51	0.006553	0.328554
hsa-miR-548ae-2-5p	1.10	2.14	0.007103	0.328554
hsa-mir-3138	− 1.14	0.45	0.007248	0.328554
hsa-miR-6884-5p	0.58	1.49	0.008981	0.385731
hsa-miR-25-5p	0.44	1.36	0.010531	0.404056
hsa-miR-320b-1-3p	0.43	1.35	0.010797	0.404056
hsa-miR-4772-3p	− 0.60	0.66	0.011461	0.404056
hsa-miR-3064-5p	0.56	1.47	0.011532	0.404056
hsa-mir-3607	− 0.53	0.69	0.012026	0.404056
hsa-miR-421-3p	− 0.25	0.84	0.013088	0.404056
hsa-mir-3922	0.50	1.42	0.013536	0.404056
hsa-miR-3605-5p	0.46	1.37	0.014781	0.404056
hsa-miR-4649-3p	− 0.53	0.69	0.01502	0.404056
hsa-miR-30a-3p	0.67	1.59	0.015235	0.404056
hsa-miR-542-3p	0.54	1.46	0.015267	0.404056
hsa-miR-4732-5p	0.42	1.34	0.01535	0.404056
hsa-miR-337-3p	− 0.51	0.70	0.016418	0.412266
hsa-miR-320d-1-3p	0.47	1.38	0.017108	0.412266
hsa-mir-1273 g	0.36	1.29	0.017178	0.412266
hsa-miR-3913-1-3p	− 0.34	0.79	0.018048	0.420787
hsa-miR-3691-3p	− 0.35	0.78	0.020256	0.459135
hsa-miR-5701-1-5p	− 0.57	0.67	0.023849	0.475508
hsa-miR-589-3p	− 0.26	0.84	0.023928	0.475508
hsa-mir-202	− 0.62	0.65	0.02398	0.475508
hsa-miR-23b-5p	0.33	1.26	0.02412	0.475508
hsa-miR-3138-3p	0.46	1.38	0.024643	0.475508
hsa-miR-641-5p	− 0.32	0.80	0.025083	0.475508
hsa-miR-15b-5p	− 0.25	0.84	0.025333	0.475508
hsa-mir-1248	− 0.62	0.65	0.026133	0.475508
hsa-miR-664b-5p	0.43	1.34	0.026223	0.475508
hsa-miR-579-5p	0.33	1.26	0.027033	0.479535
hsa-miR-2277-3p	0.37	1.29	0.027747	0.481733
hsa-miR-1287-5p	0.47	1.38	0.031054	0.525366
hsa-miR-627-3p	− 0.29	0.82	0.032362	0.525366
hsa-miR-423-5p	0.30	1.23	0.032829	0.525366
hsa-miR-92b-5p	0.41	1.33	0.032835	0.525366
hsa-miR-548n-3p	− 0.40	0.76	0.035717	0.541575
hsa-miR-3607-3p	− 0.51	0.70	0.035911	0.541575
hsa-miR-146b-5p	− 0.29	0.82	0.036279	0.541575
hsa-miR-3667-5p	0.59	1.50	0.03678	0.541575
hsa-miR-185-3p	0.31	1.24	0.03858	0.541575
hsa-miR-10a-5p	− 0.41	0.75	0.038723	0.541575
hsa-miR-628-5p	− 0.30	0.81	0.039484	0.541575
hsa-miR-190a-5p	0.52	1.44	0.04009	0.541575
hsa-miR-1284-5p	− 0.24	0.84	0.04149	0.541575
hsa-let-7a-3	0.50	1.41	0.042166	0.541575
hsa-miR-4742-3p	− 0.32	0.80	0.04264	0.541575
hsa-miR-196a-1-5p	0.80	1.74	0.04283	0.541575
hsa-miR-6513-3p	− 0.25	0.84	0.043181	0.541575
hsa-miR-1294-5p	0.39	1.31	0.043499	0.541575
hsa-miR-3130-1-5p	− 0.27	0.83	0.043804	0.541575
hsa-miR-643-3p	− 0.38	0.77	0.04469	0.544284
hsa-miR-6729-3p	0.40	1.32	0.045509	0.546106
hsa-mir-1229	0.48	1.40	0.046396	0.548684
hsa-miR-654-3p	− 0.46	0.73	0.048297	0.563006
hsa-miR-128-1-3p	− 0.23	0.85	0.049922	0.56594

Log₂FC log₂ fold change, directionality denoted by + (upregulated) or – (downregulated) value when comparing AD to controls

^aMagnitude of fold change between AD compared to controls