Table 3.

Multivariate Cox regression analysis on 5-year overall and disease-free survival

Parameter	Overall survival			Disease-free survival
	Hazard ratio	95% Cl†	P*	Hazard ratio	95% Cl†	P*
ATR (fibroblasts)	14.708	2.693–80.332	0.0019	0.369	0.151–0.900	0.0285
Tumor size	0.665	0.084–5.244	0.6985	1.018	0.276–3.759	0.9790
Age	0.878	0.802–0.962	0.0051	1.027	0.989–1.067	0.1642
Stage	95.600	5.109–1788.693	0.0023	0.471	0.112–1.975	0.3035
Grade	0.868	0.187–4.030	0.8564	1.363	0.647–2.874	0.4155
HR_ Status ER(+ve)/Her2(−ve)	8.981	0.774–104.259	0.0793	0.649	0.283–1.489	0.3079
HR_ Status ER(−ve)/Her2(+ve)	31.436	2.109–468.544	0.0124	0.412	0.102–1.662	0.2096
HR_ Status ER(−ve)/Her2(−ve)	30.258	2.054–445.803	0.0130	0.592	0.161–2.231	0.4445
ER_PR_Status ER(+ve)/PR(−ve)	0.074	0.003.009–1.771	0.1080	0.759	0.110–5.254	0.7802
ER_PR_Status ER(+ve)/PR(+ve)	0.845	0.122–5.837	0.8640	0.726	0.169–3.108	0.6655
Parameter	Overall survival			Disease-free survival
	Hazard ratio	95% Cl†	P*	Hazard ratio	95% Cl†	P*
ATR (epithelial cells)	10.242	1.745–60.111	0.0100	0.834	0.436–1.598	0.5849
Tumor size	0.049	0.006–0.425	0.0062	1.459	0.402–5.301	0.5659
Age	0.880	0.804–0.962	0.0050	1.028	0.989–1.068	0.1637
Stage	257.360	13.853–4781.270	0.0002	0.334	0.084–1.325	0.1188
Grade	1.205	0.266–5.452	0.8083	1.379	0.672–2.832	0.3807
HR_ Status ER(+ve)/Her2(−ve)	2.731	0.382–19.517	0.3166	0.633	0.266–1.505	0.3004
HR_ Status ER(−ve)/Her2(+ve)	1.456	0.146–14.486	0.7488	0.657	0.196–2.207	0.4973
HR_ Status ER(−ve)/Her2(−ve)	4.817	0.459–50.592	0.1901	0.655	0.193–2.225	0.4973
ER_PR_Status ER(+ve)/PR(−ve)	0.901	0.465–25.058	0.9296	1.187	0.207–6.820	0.8474
ER_PR_Status ER(+ve)/PR(+ve)	10.511	0.671–164.698	0.2275	1.021	0.983–1.061	0.2730