Table 3.

Comparison of the adverse events in the full analysis set

Adverse events	Treatment group	Control group	p value
Total	65 (45.8%)	77 (54.2%)	0.154
Abnormal liver function	32(22.5%)	32(22.5%)	1.000
Renal dysfunction	8 (5.6%)	11 (7.7%)	0.476
Headache	1 (0.7%)	1 (0.7%)	1.000
Nausea	6 (4.2%)	5 (3.5%)	0.758
Vomiting	2 (1.4%)	3 (2.1%)	0.652
Diarrhea	8 (5.6%)	19 (13.4%)	0.026
Loss of appetite	8 (5.6%)	6 (4.2%)	0.584