Table 4.
Factors Associated with RFS After CT-PCRA for EHCC
| Factor | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age (years) | 0.932 (0.427, 3.336) | 0.782 | … | … |
| <65 | 21 | 21 | ||
| ≥65 | 12 | 12 | ||
| Gender | 1.478 (0.058, 3.362) | 0.246 | … | … |
| Male | 26 | 26 | ||
| Female | 7 | 7 | ||
| Comorbidities | 1.478 (0.058, 3.362) | 0.246 | ||
| Positive | 20 | 20 | ||
| Negative | 13 | 13 | ||
| Cirrhosis | 1.478 (0.058, 3.362) | 0.246 | ||
| Positive | 31 | 31 | ||
| Negative | 2 | 2 | ||
| Hepatitis B surface antigen | 2.227 (0.568, 4.447) | 0.459 | … | … |
| Positive | 29 | 29 | ||
| Negative | 4 | 4 | ||
| Tumor size (cm) | 2.916 (1.562, 5.274) | 0.034 | 3.302 (2.232, 8.293) | 0.012 |
| <3 | 21 | 21 | ||
| ≥3 | 12 | 12 | ||
| α-fetoprotein level (ng/mL) | 0.884 (0.271, 1.193) | 0.445 | … | … |
| ≤200 | 27 | 27 | ||
| >200 | 6 | 6 | ||
| Child–Pugh grade | 1.012 (0.332, 3.192) | 0.093 | … | … |
| A | 31 | 31 | ||
| B | 2 | 2 | ||
| ALBI grade | 1.398 (0.950, 2.058) | 0.401 | … | … |
| 1 | 27 | 27 | ||
| 2–3 | 6 | 6 | ||
| Sessions | 1.478 (0.058, 3.362) | 0.246 | … | … |
| 1 | 30 | 30 | ||
| >1 | 3 | 3 | ||
Notes: Data in parentheses are 95% confidence intervals. Variables were analyzed by a univariate model of Cox Proportional Hazard Test; those with a P-value < 0.05 were showed here and were forwarded to the multivariate analysis.
Abbreviations: RFS, recurrence-free survival; EHCC, subcardiac hepatocellular carcinoma; CT-PCRA, computed tomography-guided percutaneous cryoablation; ALBI, albumin–bilirubin.