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. 2020 May 12;12:3343–3352. doi: 10.2147/CMAR.S250772

Figure 3.

Figure 3

C-MET is a direct downstream target of miR-340. (A) Schematic of the construction of wild-type or mutant c-MET 3ʹ-UTR vectors is illustrated. (B) Relative luciferase activity was analyzed in U251 and LN229 cells. Firefly luciferase vector was used as an internal control. (C) Western blot results of c-MET protein in U251 and LN229 cells transduced with miR-340 and negative control. (D) The representative IHC pictures showed the c-MET protein expression in tissue with high or low miR-340 expression. (E) The relative expression level of c-MET by IHC in groups with high or low miR-340. **P<0.01.