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. 2020 Apr 16;48(9):4681–4697. doi: 10.1093/nar/gkaa209

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Lower levels of miRNA-targeting of upstream miRNA biogenesis and downstream regulatory effectors. The histogram in Figure 1 is used to show the contrast in the levels of targeting by miRNAs between two groups of mRNAs. The miRNA biogenesis () and miRNA targeting machinery () are shown in (A), and the downstream regulatory effectors () and miRNA targeting machinery () in (B). In (B), CNOTs 3 and 9–11 share one data point, as they have the same number of miRNA sites. The Mann–Whitney–Wilcoxon test P-values of the contrast between two groups of mRNAs are specified inside both plots.

Inline graphic — Lower levels of miRNA-targeting of upstream miRNA biogenesis and downstream regulatory effectors. The histogram in Figure 1 is used to show the contrast in the levels of targeting by miRNAs between two groups of mRNAs. The miRNA biogenesis () and miRNA targeting machinery () are shown in (A), and the downstream regulatory effectors () and miRNA targeting machinery () in (B). In (B), CNOTs 3 and 9–11 share one data point, as they have the same number of miRNA sites. The Mann–Whitney–Wilcoxon test P-values of the contrast between two groups of mRNAs are specified inside both plots.