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. 2020 Mar 30;48(9):4946–4959. doi: 10.1093/nar/gkaa189

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — The overall structure of hcLRS. (A) Overall structure of hcLRS shown in cartoon. The Rossmann-fold domain (AD, green), the CP core & CP1 hairpin (pink), the CP1 editing domain (cyan), the CP2 domain (blue), the eukaryotic leucyl-specific domains 1 (magenta) and 2 (violet-purple), the SC-fold domain (red), the α-helix bundle domain (slate) and the VC domain (orange and sand); (B) A diagram shown the domains and motifs of hcLRS, PhLRS and TtLRS; (C) Structural comparison of hcLRS, PhLRS and TtLRS shown in cartoon from a same view.