Table 1.
Results for leave-one-out cross-validation
| Complete proteome | Prophage subset | ||||||
|---|---|---|---|---|---|---|---|
| Accession No. | Anti-CRISPR family | Proteome size | BLAST rank | AcRanker rank | Proteome Size | BLAST rank | AcRanker rank |
| YP_007392738.1 | AcrIE1 | 57 | 33 | 1 | - | - | - |
| YP_007392439.1 | AcrIE2 | 54 | 18 | 2 | - | - | - |
| YP_950454.1 | AcrIE3 | 52 | 17 | 1 | - | - | - |
| NP_938238.1 | AcrIE4 | 54 | 11 | 1 | - | - | - |
| YP_007392342.1 | AcrIF1 | 56 | 21 | 11 | - | - | - |
| YP_002332454.1 | AcrIF2 | 51 | 34 | 1 | - | - | - |
| YP_007392440.1 | AcrIF3 | 54 | 5 | 1 | - | - | - |
| YP_007392799.1 | AcrIF4 | 57 | 36 | 3 | - | - | - |
| YP_007392740.1 | AcrIF5 | 57 | 26 | 19 | - | - | - |
| WP_043884810.1 | AcrIF6 | 6095 | 1 | 80 | 361 | 1 | 15 |
| WP_019933870.1 | AcrIF6 | 3045 | 1 | 13 | 72 | 1 | 1 |
| WP_014702809.1 | AcrIF6 | 2689 | 1 | 130 | 57 | - | - |
| ACD38920.1 | AcrIF7 | 57 | 20 | 1 | - | - | - |
| AFC22483.1 | AcrIF8 | 68 | 30 | 1 | - | - | - |
| WP_031500045.1 | AcrIF9 | 4928 | 198 | 333 | 37 | - | - |
| KEK29119.1 | AcrIF10 | 3552 | 189 | 17 | 70 | 23 | 2 |
| AEO04364.1 | AcrIIA1 | 2951 | 183 | 770 | 146 | 60 | 87 |
| AEO04363.1 | AcrIIA2 | 2951 | 210 | 16 | 146 | 34 | 3 |
| AEO04689.1 | AcrIIA4 | 2951 | 59 | 21 | 146 | 9 | 4 |
| ASD50988.1 | AcrIIA5 | 54 | 5 | 8 | - | - | - |
Each row of the table indicates which Acr was excluded from the training dataset and used as a test dataset, and each number displayed is the ranking of the known Acr received from the indicated test proteome using either the blastp search against all other known Acrs (BLAST) or AcRanker. The Acrs from bacterial proteomes—AcrIF6, AcrIF9, AcrIF10, AcrIIA1, AcrIIA2 and AcrIIA4—were also ranked using only the subset of proteins predicted to reside within prophages as predicted by PHASTER (49). Two Acrs from bacterial proteomes did not occur in the predicted prophages (WP_014702809.1 and WP_031500045.1) and are indicated by dash placeholders. All three prophage proteome subset fields have been left empty for Acrs from phage proteomes.