Figure 5.
Synthetic genetic interactions of Pin1-Ala mutants. S. pombe strains bearing the indicated pin1 alleles in combination with ppn1Δ or swd22Δ (A) and rpb1-CTD-Y1F (B) were spot-tested for growth on YES agar at the indicated temperatures. As noted below panel A, pin1-Y22A-W33A and pin1-C125A were lethal in the ppn1Δ and swd22Δ backgrounds.
