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. 2020 Apr 13;48(9):4811–4826. doi: 10.1093/nar/gkaa212

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 7. — Nexus between Pin1 and inositol pyrophosphate (IPP) status. (A) Pin1 is essential in the absence of IP8. S. pombe strains with genotypes as specified were spot-tested for growth on YES agar at the indicated temperatures. (B) Lethality of asp1-H397A aps1Δ is rescued by pin1Δ. Cells with the indicated genotypes were grown in liquid culture in YES medium at 30°C and assayed for Pho1 acid phosphatase activity.