Figure 6.

ASO-29 rescues behaviorally-relevant vestibular function that is sustained longitudinally. (A–D) Thirty second activity traces from a representative of each of the four treatment groups. (E–J) Graphs show average values ± SEM for: (E) distance traveled; (F) average velocity; (G) number of 360 degree rotations; (H) latency to fall; (I) swim score (individuals were plotted so that the zero scores of ASO-C and untreated mutants are readily detected on the X-axis); (J) average number of nose translocations past the shoulder line per trial (i.e., reaching caudally). One-way ANOVA with Tukey's Multiple Comparison Test; **P < 0.01 with comparisons indicated by the hatched bars above each panel. n values in (E) apply to (F) and (G); n values in (H) apply to (I) and (J). The 180 day vestibular function test data are presented in Supplementary Figure S9.