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. 2020 Mar 6;48(9):e52. doi: 10.1093/nar/gkaa143

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Capturing RNA-binding proteins of NORAD by CRUIS. (A) The target RBPs were determined by a moderated t-test (P value < 0.05) and fold change (fold change > 3). (B) Bar plot of log2 fold change (log₂FC) of the identified proteins in NORAD interactome by CRIUS. (C) The top 15 GO-enriched biological processes of proteins in NORAD interactome by CRUIS (red dots), the negative control (green dots) and combined datasets (light blue dots). (P-value < 0.01, P.adjust < 0.05). (D) Subcellular distribution of the identified proteins in NORAD interactome by CRIUS. (E) Comparison of NORAD interactome by CRUIS with the two public datasets: RAP MS (16) and StarBase v2.0 database (17).