Table 5.
Replication results of the top nine regions identified in the GWAS for the general tests of association
| SNP name | Chromosome (location in bp) | Alleles (frequency of allele 1) | Multiple BMI P value in the replication sample (βa) | Maximum BMI P value in the replication sample (βa) |
|---|---|---|---|---|
| rs6441552 | 3 (101979305) | A/G (0.74) | 0.0650 (0.0139) | 0.8959 (0.0010) |
| rs17612333 | 4 (169566959) | A/C (0.35) | 0.0014 (0.0220) | 0.0580 (0.0134) |
| rs4711689 | 6 (41800790) | C/T (0.31) | 0.5346 (−0.0044) | 0.5284 (−0.0045) |
| rs9381282 | 6 (44116303) | G/T (0.46) | 0.0008 (−0.0223) | 0.0912 (−0.0114) |
| rs2670134 | 6 (52669733) | A/G (0.33) | 0.0533 (0.0134) | 0.2206 (0.0086) |
| rs9342220 | 6 (90828533) | A/G (0.29) | 0.1488 (0.0108) | 0.2485 (0.0088) |
| rs11652094 | 17 (21112882) | C/G (0.73) | 0.0120 (0.0183) | 0.1320 (0.0113) |
| rs1418029 | 20 (2008151) | C/T (0.12) | 0.0059 (0.0295) | 0.0526 (0.0217) |
| rs4811346 | 20 (50456516) | G/T (0.19) | 0.0061 (0.0224) | 0.8697 (−0.0014) |
bp, base pairs; GWAS, genome-wide association study; SNPs, single-nucleotide polymorphisms.
a
Regression coefficient per copy of allele 1 (in log (BMI) units).