Table 1.
Baseline characteristics
| MESA (n = 6715) | ARIC (n = 9250) | HNR (n = 4177) | EPIC-NL (n = 25 833) | EPIC-Norfolk (n = 23 548) | |
|---|---|---|---|---|---|
| Age (years) | 62 (53–70) | 62 (58–67) | 59 (52–65) | 55 (51–60) | 59 (52–67) |
| Gender (male) | 53% | 42% | 47% | 17% | 44% |
| Race | |||||
| Caucasian | 39% | 78% | 100% | 96% | 100% |
| African American | 28% | 22% | 0% | 0% | 0% |
| Other | 34% | 0% | 0% | 4% | 0% |
| Parental history of premature MI | 15% | 16% | 22% | 13% | 7% |
| Body mass index (kg/m2) | 28 (25–31) | 28 (25–31) | 27 (25–30) | 26 (23–28) | 26 (24–28) |
| Non-HDL (mmol/L) | 3.7 (3.1–4.2) | 3.9 (3.3–4.5) | 4.4 (3.8–5.1) | 4.3 (3.6–5.0) | 4.7 (3.9–5.5) |
| Systolic blood pressure (mmHg) | 124 (111–140) | 125 (114–138) | 132 (118–145) | 129 (117–141) | 134 (123–147) |
| Smoking status | |||||
| Current | 14% | 14% | 23% | 27% | 12% |
| Former | 37% | 42% | 33% | 35% | 42% |
| Diabetes mellitus | 14% | 15% | 12% | 3% | 2% |
Data are presented as median (25th–75th percentile) or frequency (%).
EPIC-NL is assumed to be 96% Caucasian based on genetic analyses. HNR is assumed to be 100% Caucasian.
MI, myocardial infarction; non-HDL, non-high-density lipoprotein cholesterol.