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. 2019 Aug 10;69(5):911–919. doi: 10.1136/gutjnl-2019-319146

Figure 4.

Figure 4

EXE-RM-LNC treatment impacts lipid homeostasis. (A) Liver weight (g). (B) Morphology of the liver in H&E-stained sections following a chronic/long-term EXE treatment in diabetic and obese mice. Representative liver H&E staining (scale bar: 100 µm). (C) Representative liver oil red O staining (scale bar: 100 µm), oil red O staining expressed in percentage of area stained and mean lipid droplet size (μm2, n=5–7). (D) Liver total lipid content (mg-1 per 100 mg of tissue). (E) Liver triglycerides (nmol mg−1). (G) Liver cholesterol (nmol mg−1). Data with different superscript letters (A–F) are significantly different (p<0.05). P values in (A) were determined following one-way analysis of variance with Tukey’s post hoc test. P values in (C–F) were determined by the Kruskal-Wallis test followed by Dunn’s post hoc test.