Table 2.
Time | Group | Total score | 1 | 2 | 3 | 4 |
0 | Placebo | 315.2±77.1 | 107.5±46.1 | 55.5±24.7 | 76.1±20.7 | 75.4±19.8 |
30 g FMT | 311.8±76.8 | 111.1±42.8 | 51.0±25.8 | 76.4±19.2 | 75.6±17.8 | |
60 g FMT | 313.3±87.3 | 106.5±45.8 | 55.0±25.4 | 78.6±18.1 | 75.6±20.8 | |
2 weeks | Placebo | 278.7±124.7 | 88.1±57.0 | 51.2±30.5 | 62.6±28.5 | 64.5±27.5 |
30 g FMT | 244.0±98.5** | 84.4±49.3 | 35.0±24.8** | 53.3±25.7** | 54.4±25.2* | |
60 g FMT | 184.6±96.3*** | 58.9±41.9**† | 32.7±26.0*** | 43.6±26.0*** | 48.2±26.4** | |
1 month | Placebo | 299.5±106.1 | 102.0±51.2 | 53.5±27.4 | 70.3±25.1 | 69.1±26.3 |
30 g FMT | 213.4±100.1*** | 97.7±47.8* | 36.9±22.8*** | 49.4±28.9*** | 50.9±29.1*** | |
60 g FMT | 186.8±107.0*** | 66.8±50.8*** | 33.7±24.6*** | 40.4±28.4*** | 46.4±26.8*** | |
3 months | Placebo | 307.0±87.1 | 112.0±69.7 | 56.8±31.8 | 73.1±22.3 | 71.7±22.0 |
30 g FMT | 186.3±109.0*** | 69.4±48.5*** | 30.5±21.7*** | 44.6±29.7*** | 45.3±30.9*** | |
60 g FMT | 166.8±117.9*** | 56.5±47.5*** | 30.4±26.4*** | 35.6±26.2*** | 40.2±27.1*** |
IBS-SSS items: 1, abdominal pain; 2, abdominal distension; 3, dissatisfaction with bowel habits; 4, interference with quality of life.
Data are mean±SD values.
*p<0.05;**p<0.01; ***p<0.001 compared with placebo.
†p<0.05 compared with 30 g FMT.
FMT, faecal microbiota transplantation; IBS, irritable bowel syndrome; IBS-SSS, IBS Severity Scoring System.