Table 4.

IBS-QoL total scores and scores in the eight domains of the scale in placebo and FMT-treated patients

Time	Group	Total score	1	2	3	4	5	6	7	8
0	Placebo	117.8±19.7	27.3±5.8	23.6±5.8	11.9±2.7	10.6±2.6	7.2±2.6	15.0±3.1	7.8±1.7	11.2±2.5
	30 g FMT	109.1±22.7	26.2±6.9	20.0±5.9**	11.2±3.4	10.3±2.8	5.9±2.8	13.6±3.5	7.5±2.1	10.8±2.6
	60 g FMT	113.4±22.4	27.4±6.7	21.4±5.5	11.5±2.8	10.6±2.7	6.7±2.8	14.1±3.4	7.7±1.7	10.8±2.8
2 weeks	Placebo	122.4±28.1	29.1±6.5	23.0±4.9	12.3±3.33	11.3±2.7	8.0±3.4	14.7±4.6	7.6±2.6	11.1±3.5
	30 g FMT	118.0±23.0	28.6±6.7	20.4±5.8*	13.3±3.2	11.3±3.1	7.1±3.1	14.3±3.4	7.8±2.0	10.9±2.1
	60 g FMT	124.5±25.1	31.1±6.6	23.3±5.9†	13.4±3.7	12.0±2.7	8.3±2.8	15.5±3.5	8.1±1.9	11.7±2.7
1 month	Placebo	122.9±25.4	29.2±7.7	23.1±4.8	12.7±4.2	12.3±2.4	8.6±2.9	14.7±3.4	7.0±2.3	11.4±2.8
	30 g FMT	121.6±23.9	29.5±7.1	21.8±4.8	13.2±3.7	11.6±2.5	7.2±2.9*	15.8±3.1	7.9±1.6	11.5±2.4
	60 g FMT	127.7±25.5	31.1±6.7	23.0±5.1	13.9±3.5	12.1±2.4	8.6±3.3†	15.1±3.9	8.2±2.0**	11.7±2.8
3 months	Placebo	113.0±24.3	27.2±6.3	21.2±4.6	12.1±3.0	12.8±6.3	7.1±3.0	13.6±3.8	7.3±2.3	10.4±2.5
	30 g FMT	131.5±21.6***	32.1±6.9**	24.1±5.2**	14.0±3.0**	12.6±2.9	8.8±3.2*	16.1±2.6***	8.2±1.6*	12.6±1.8****
	60 g FMT	132.0±24.8***	32.5±6.7**	24.0±4.7**	14.5±3.4***	12.2±2.2	9.6±3.6***	15.7±3.5**	8.3±1.6*	12.1±2.6***

IBS-QoL domains: 1, dysphoria; 2, interference with daily activities; 3, body image; 4, health worries; 5, food avoidance; 6, social reaction; 7, sexual function; 8, impact on relationships.

*p<0.05; **p<0.01; ***p<0.001; ****p<0.0001 compared with placebo.

†p<0.05 compared with 30 g FMT.

FMT, faecal microbiota transplantation; IBS, irritable bowel syndrome; IBS-QoL, IBS Quality of Life.