Table 4.

Physiology for all patients with Combowire data including post-PCI Combowire results pressure following Core Laboratory analysis (n=89/93), flow and resistance data for all randomised patients with Combowire data according to treatment group

Baseline invasive physiology for entire cohort
	N	Minimum	Maximum	Mean (SD)
FFR	89	0.75	0.82	0.78 (0.02)
HMR	89	0.9	6.9	2.10 (0.84)
HSR	89	0.15	2.00	0.52 (0.25)
CFVR	89	1.3	5.0	2.41 (0.75)

By randomised group
		N	Mean	SD
FFR	OMT	38	0.78	0.02
	PCI	51	0.78	0.02
HMR	OMT	38	2.21	0.74
	PCI	51	2.01	0.91
HSR	OMT	38	0.55	0.21
	PCI	51	0.50	0.27
CFVR	OMT	38	2.35	0.72
	PCI	51	2.45	0.77

Invasive physiology pre-PCI and post-PCI
	Pre-PCI	Post-PCI	N	P value
FFR	0.77 (0.02)	0.90 (0.06)	41	0.001
HMR	2.07 (0.98)	2.31 (0.95)	41	0.02
HSR	0.51 (0.29)	0.20 (0.18)	40	0.001
CFVR	2.34 (0.73)	2.28 (0.69)	40	0.548

CFVR, coronary flow velocity reserve; FFR, fractional flow reserve; HMR, hyperaemic microvascular resistance; HSR, Hyperaemic Stenosis Resistance Index; N, total number of patients; OMT, optimal medical therapy group; PCI, percutaneous coronary intervention with medical therapy group.