Table 1.
Summary of clinical parameters and clinical course in seven patients with suspected SARS-CoV-2 after urological surgerya.
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | |
|---|---|---|---|---|---|---|---|
| Gender | Male | Male | Male | Female | Female | Female | Male |
| Indication for PO SARS-CoV-2 NS | Pyrexia, dry cough, malaise | Pyrexia, dry cough, dyspnoea | Dry cough, dyspnoea, malaise | Pyrexia, dry cough | Pyrexia | Pyrexia | Pyrexia, dry cough |
| SARS-CoV-2 Dx | Yes | Yes | Yes | No (atelectasis) | No (atelectasis) | No (pyelonephritis) | No (atelectasis) |
| Positive SARS-CoV-2 NS | Yes | Yes | No | No | No | No | No |
| Age (yr) | 53 | 82 | 67 | 70 | 49 | 56 | 77 |
| Procedure | LN | TURBT | RARP | LN | Cystectomy | Cystectomy | Nephroureterectomy |
| Comorbidities | HTN | HTN, ex-smoker | Smoker | HTN, provoked DVT | Thrombophilia | HTN | T1DM, HTN |
| ASA score | 3 | 3 | 2 | 2 | 3 | 2 | 3 |
| BMI (kg/m2) | 33.6 | 29.6 | 31.6 | 35.5 | 34.8 | 25 | 33 |
| Time to Dx after surgery (d) | 14 | 4 | 20 | 2 | 4 | 26 | 2 |
| Onset to Dx (d) | 3 | 6 | 1 | 1 | 1 | 1 | 1 |
| Date of SARS-CoV-2 Dx | April 12, 2020 | April 18, 2020 | April 9, 2020 | N/A | N/A | N/A | N/A |
| ICU support required | No | No | Yes | No | No | No | No |
| Fever | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Highest fever (°C) | 39.1 | 40 | 35.5 | 38.2 | 38.5 | 39.1 | 38.2 |
| Diarrhoea | No | No | No | No | No | No | No |
| Highest CRP (mg/l) | 269 | 272.9 | 107 | Not measured | 282 | 186 | 224 |
| Lymphopenia | No | Yes | No | No | Yes | Yes | Yes |
| Elevated sCr (μmol/l) | 176 | 194 | 161 | 127 | No | No | 258 |
| SARS-CoV-2–related events | Viral pneumonia: bilateral pleural effusions and patchy GGO on CXR | Viral pneumonia: GGO changes involving all lobes of both lungs on CT, MI | Overwhelming ARDS within 4 h of readmission | N/A (atelectasis) | N/A (atelectasis) | N/A | N/A |
| SARS-CoV-2 treatment | NIV (CPAP/BiPAP) | NIV (CPAP/BiPAP) | Ventilated | N/A | N/A | N/A | N/A |
| SARS-CoV-2 outcomes | Discharged after 27 d | Current inpatient (20 d after Dx) | Mortality | N/A | N/A | N/A | N/A |
ARDS = acute respiratory distress syndrome; ASA = American Society of Anesthesiologists; BiPAP = bilevel positive airway pressure; BMI = body mass index; CPAP = continuous positive airway pressure; CRP = C-reactive protein; CT = computed tomography; CXR = chest X-ray; DVT = deep vein thrombosis; Dx = diagnosis; GGO = ground glass opacity; HTN = hypertension; ICU = intensive care unit; LN = laparoscopic nephrectomy; MI = myocardial infarction; N/A = not applicable; NIV = noninvasive ventilation; NS = nasopharyngeal swab; PO = postoperative; RARP = robot-assisted radical prostatectomy; sCr = serum creatinine; T1DM = type 1 diabetes mellitus; TURBT = transurethral resection of bladder tumour.
Patients 1 and 2 had a positive PO NS for SARS-CoV-2. Patient 3 had a clinical diagnosis of SARS-CoV-2. Patients 4–7 had one or more symptoms of SARS-CoV-2 and a negative NS for SARS-CoV-2.