Table 1.
TH immunoreactivity in the striatum of vehicle- and 6-OHDA-injected mice
Mouse Line/Cell Type | vehicle: TH immunoreactivity (%) | 6-OHDA: TH immunoreactivity (%) | p - value |
---|---|---|---|
A2A-cre/D2-SPNs | 101, 98–105; n = 6 | 4, 11–4; n = 9 | p = 0.0004* |
A2A-cre/GPe | ————————— | 4, 11–5; n = 8 | ————— |
PV-cre/PV GPe | 103, 96–105; n = 7 | 1, −11–3; n = 6 | p = 0.0012* |
PV-cre/STN | 103, 96–106; n = 6 | 0, −16–1; n = 5 | p = 0.0043* |
PV-cre X Ai9/PV GPe | 99, 99–131; n = 3 | 15, 29–6; n = 7 | p = 0.0167* |
GABRR3-cre/GPe | 102, 96–104; n = 3 | −3, −34-−2; n = 4 | p = 0.0571 |
TH immunoreactivity in the ipsilateral dorsal striatum expressed as a percentage of immunoreactivity in the non-injected contralateral hemisphere, stratified by mouse line and recorded cell type.
p < 0.05 (MWU).