Table 3.
Spectral analysis of LFPs in the GPe and STN during cortical SWA and ACT in vehicle- and 6-OHDA-injected mice
| Frequency Band (Hz) | vehicle: Relative Power | 6-OHDA: Relative Power | p - value | vehicle: Peak Frequency (Hz) | 6-OHDA: Peak Frequency (Hz) | p - value | n vehicle/6-OHDA) |
|---|---|---|---|---|---|---|---|
| GPe 0.5–1.5 (SWA) | 0.408, 0.248 – 0.446 | 0.272, 0.135 – 0.347 | 0.0014 | 1.22, 0.977 – 1.34 | 0.977, 0.732 – 1.31 | 0.0749 | 25/48 |
| GPe 10–39.9 (SWA) | (0.912, 0.504 – 1.67) × 10−2 | (0.548, 0.281 – 0.124) × 10−2 | 0.0705 | 10.6, 10.0 – 11.8 | 10.4, 10.2 – 11.4 | 0.9464 | 25/48 |
| GPe 40–250 (SWA) | (4.06, 2.19 −6.90) × 10−3 | (3.33, 2.18 −9.48) × 10−3 | 0.7509 | 180, 59.8 – 180 | 180, 60.1 – 180 | 0.4841 | 25/48 |
| GPe 0.5–1.5 (ACT) | (3.61, 1.97 – 8.47) × 10−2 | (4.09, 2.40 – 8.58) × 10−2 | 0.5502 | 0.610, 0.610 – 1.22 | 0.610, 0.610 – 0.732 | 0.9704 | 21/24 |
| GPe 10–39.9 (ACT) | (2.66, 1.74 – 4.98) × 10−2 | (3.82, 1.29 – 4.64) × 10−2 | 0.8659 | 11.2, 10.3 – 12.8 | 10.7, 10.1 – 11.8 | 0.2312 | 21/24 |
| GPe 40–250 (ACT) | (1.48, 0.611 – 2.82) × 10−2 | (1.61, 0.573 −3.29) × 10−2 | 0.5963 | 180, 43.3 – 180 | 60.2, 45.5 – 180 | 0.5834 | 21/24 |
| STN 0.5–1.5 (SWA) | 0.194, 0.103 – 0.336 | 0.0878, 0.0506 – 0.161 | 0.0754 | 0.977, 0.763 – 1.31 | 1.34, 1.22 – 1.47 | 0.0303 | 8/11 |
| STN 10–39.9 (SWA) | (1.76, 0.622 – 2.90) × 10−2 | (0.913, 0.78 – 1.42) × 10−2 | 0.4421 | 11.5, 10.7 – 12.4 | 10.9, 10.3 – 12 | 0.5282 | 8/11 |
| STN 40–250 (SWA) | (2.19, 0.601 – 3.48) × 10−2 | (11.2, 0.71 – 1.47) × 10−2 | 0.3100 | 120, 60.0 – 180 | 180, 59.8 – 180 | 0.9525 | 8/11 |
| STN 0.5–1.5 (ACT) | (5.43, 1.66 −9.75) × 10−2 | (5.32, 3.92 – 6.61) × 10−2 | 0.9015 | 0.610, 0.610 – 0.610 | 0.610, 0.610 – 0.732 | 0.7308 | 7/7 |
| STN 10–39.9 (ACT) | (1.98, 0.853 – 3.39) × 10−2 | (1.3, 0.754 – 2.65) × 10−2 | 0.4557 | 11.2, 10.7 – 13.4 | 23.2, 14.8 – 30.5 | 0.0390 | 7/7 |
| STN 40–250 (ACT) | (2.40, 0.435 – 4.10) × 10−2 | (1.24, 1.22 – 2.14) × 10−2 | 0.8048 | 180, 59.8 – 180 | 180, 45.3 – 180 | 0.6503 | 7/7 |
Relative power and peak frequency in the LFPs of vehicle- and 6-OHDA-injected mice during cortical SWA or ACT in the 0.5–1.5 Hz, 10–39.9 Hz, and 40–250 Hz frequency bands. Power in each band was normalized to the power in the 0–250 Hz range.
*,
p < 0.05 (MWU).