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. 2019 May 25;59(4):1399–1411. doi: 10.1007/s00394-019-01993-8

Table 3.

Vitamin B status and markers of inflammation according to age-corrected RTL and RTL quartiles

Age-corrected RTL quartiles 1st (n = 739)
< 0.0140
2nd (n = 748)
0.0141–0.0280
3rd (n = 738)
0.0281–0.0509
4th (n = 743)
> 0.0510
p value p value 1–3 vs 4
HCY (µmol/L) 12.8 (8.5–20.1) 12.4 (8.1–19.9) 12.2 (7.9–21.2) 11.7 (7.8–18.6) < 0.001 < 0.001
12.5 (8.1–20.3)
Vitamin B6 (µg/L) 8.8 (3.7–21.7) 8.6 (3.4–22.4) 8.4 (3.4–21.7) 9.7 (3.6–23.6) 0.004 0.001
8.6 (3.5–21.9)
hs-CRP (mg/L) 3.19 (0.66–21.66) 3.54 (0.71–24.20) 3.55 (0.73–20.60) 3.05 (0.53–20.25) 0.067 0.017
3.43 (0.70–21.90)
IL-6 (pg/mL) 3.34 (1.23–11.50) 3.43 (1.22–11.95) 3.26 (1.17–11.59) 2.82 (1.07–9.87) 0.001 < 0.001
3.34 (1.21–11.59)
RTL quartiles 1st (n = 739)
< 0.8915
2nd (n = 748)
0.8916–1.7881
3rd (n = 738)
1.7882–3.1088
4th (n = 743)
> 3.1089
p value p value 1–3 vs 4
HCY (µmol/L) 12.6 (8.3–19.6) 12.3 (8.14–19.7) 12.2 (7.8–20.7) 12.0 (8.1–19.1) 0.085 0.298
12.4 (8.1–20.0)
Vitamin B6 (µg/L) 9.0 (3.8–22.0) 8.6 (3.3–21.7) 8.7 (3.5–22.0) 9.4 (3.4–23.6) 0.244 0.328
8.7 (3.5–21.9)
hs-CRP (mg/L) 3.08 (0.66–21.87) 3.47 (0.66–22.90) 3.72 (0.74–19.67) 3.06 (0.59–21.50) 0.110 0.166
3.43 (0.69–21.60)
IL-6 (pg/mL) 3.31 (1.21–11.47) 3.32 (1.15–11.21) 3.33 (1.26–11.16) 2.91 (1.10–10.72) 0.026 0.001
3.32 (1.21–11.29)

Variables are reported as median (10–90th percentiles). Statistically significant differences are reported in bold