Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 8;11(4):402. doi: 10.3390/genes11040402

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Schematic representation of examples of pre-mRNAs regulated by RBM20 and PTBP1. Colored exons represent constitutively spliced exons, while white exons represent alternative exons. (a) TTN (titin), CACNA1C (Calcium Voltage-Gated Channel Subunit Alpha1 C) and CAMK2D (Calcium/Calmodulin Dependent Protein Kinase II Delta) are examples of pre-mRNAs regulated by RBM20. (b) TPM1 (α-tropomyosin), TNNT2 (Troponin T2, Cardiac Type) and ACTN1 (α-actinin) are examples of pre-mRNAs regulated by PTBP1. (c) TTN (titin) and FHOD3 (Formin Homology 2 Domain Containing 3) are examples of pre-mRNAs regulated by both PTBP1 and RBM20.