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Growth inhibition profile of perfragilin B (8b; NSC667275) in the NCI 60-cancer-cell-line panel. Each dose–response curve (5 doses tested from 0.01 to 100 µM) obtained for perfragilin B (8b) on a given cell line enables the GI50 concentration to be calculated by linear interpolation. The mean GI50 concentrations calculated on the 60 cancer cell lines is represented by the vertical black bar, which indicates that perfragilin B (8b) displays a mean GI50 concentration of ~4 µM.
