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. 2020 Apr 17;11(4):438. doi: 10.3390/genes11040438

Table 1.

Baseline characteristics of the patients included in the study.

Characteristic Apixaban 5 mg
(n = 53)
Median age (years) 70 (65;77)
Male n (%) 32 (60.4%)
BMI (kg/m2) 28 (24.6;31.3)
S (m2) 1.9 (1.6;2.1)
AF type n (%) paroxysmal 11 (20.8%)
persistent 12 (22.6%)
permanent 30 (56.6%)
Prior VKA n (%) 21 (39.6%)
CHA2DS2-VASC score 1–2 10 (18.8%)
≥3 43 (81.2%)
CrCl mL/min/1.72 m2 77.5 (64.2;90.0)
Minor bleeding n (%) 6 (11.3%)
Plasma concentrations (ng/mL) trough 132.3 (90.4;184.2)
peak 287.3 (198.6;396.8)

AF—atrial fibrillation; CrCl—creatinine clearance; BMI—body mass index, S—body surface; VKA—vitamin-K antagonists.