Table 1.
Characteristic | Apixaban 5 mg (n = 53) |
|
---|---|---|
Median age (years) | 70 (65;77) | |
Male n (%) | 32 (60.4%) | |
BMI (kg/m2) | 28 (24.6;31.3) | |
S (m2) | 1.9 (1.6;2.1) | |
AF type n (%) | paroxysmal | 11 (20.8%) |
persistent | 12 (22.6%) | |
permanent | 30 (56.6%) | |
Prior VKA n (%) | 21 (39.6%) | |
CHA2DS2-VASC score | 1–2 | 10 (18.8%) |
≥3 | 43 (81.2%) | |
CrCl mL/min/1.72 m2 | 77.5 (64.2;90.0) | |
Minor bleeding n (%) | 6 (11.3%) | |
Plasma concentrations (ng/mL) | trough | 132.3 (90.4;184.2) |
peak | 287.3 (198.6;396.8) |
AF—atrial fibrillation; CrCl—creatinine clearance; BMI—body mass index, S—body surface; VKA—vitamin-K antagonists.