Table 7.
Systemic and renal hemodynamic parameters.
| Global Cohort | AKI sCyC | NO AKI sCyC | p-Value | |
|---|---|---|---|---|
| n = 100 | n = 10 | n = 90 | ||
| Renal parameters | ||||
| Renal pulse pressure—mmHg ± SD | ||||
| Baseline | 84 ± 14 | 87 ± 18 | 83 ± 14 | 0.38 |
| Post TAVR—Day 1 | 82 ± 14 | 78 ± 14 | 82 ± 14 | 0.39 |
| Post TAVR—Day 3 | 78 ± 14 | 82 ± 19 | 78 ± 13 | 0.36 |
| Renal arterial load | ||||
| Baseline | 10 ± 3.5 | 10.1 ± 4.4 | 10 ± 3.5 | 0.87 |
| Post TAVR—Day 1 | 10 ± 3.3 | 9.8 ± 3.4 | 10 ± 3.3 | 0.76 |
| Post TAVR—Day 3 | 9.2 ± 2.5 | 9.5 ± 3.7 | 9.2 ± 2.3 | 0.72 |
| Renal arterial compliance | ||||
| Baseline | 0.11 ± 0.4 | 0.1 ± 0.6 | 0.11 ± 0.4 | 0.27 |
| Post TAVR—Day 1 | 0.11 ± 0.4 | 0.12 ± 0.5 | 0.11 ± 0.4 | 0.39 |
| Post TAVR—Day 3 | 0.12 ± 0.4 | 0.12 ± 0.4 | 0.12 ± 0.4 | 0.77 |
| Systemic parameters | ||||
| Valvuloarterial impedance—mmHg/mL/m2 | ||||
| Baseline | 4.3 ± 1.3 | 4.2 ± 1.5 | 4.3 ± 1.3 | 0.77 |
| Post TAVR—Day 1 | 3.7 ± 1.6 | 4.9 ± 4 | 3.6 ± 1.1 | 0.016 |
| Post TAVR—Day 3 | 3.2 ± 0.9 | 3.3 ± 1 | 3.2 ± 0.9 | 0.9 |
| Total arterial load | ||||
| Baseline | 2.9 ± 1 | 3 ± 1.2 | 2.9 ± 1 | 0.95 |
| Post TAVR—Day 1 | 1.7 ± 0.9 | 2.4 ± 2.3 | 1.7 ± 0.5 | 0.008 |
| Post TAVR—Day 3 | 1.5 ± 0.41 | 1.5 ± 0.5 | 1.5 ± 0.4 | 0.967 |
| Systemic arterial compliance | ||||
| Baseline | 0.9 ± 0.1 | 0.7 ± 0.3 | 1 ± 0.3 | 0.71 |
| Post TAVR—Day 1 | 1.2 ± 4.3 | 1 ± 0.5 | 1.2 ± 0.4 | 0.23 |
| Post TAVR—Day 3 | 0.7 ± 0.3 | 0.69 ± 0.2 | 0.7 ± 0.3 | 0.78 |
| Pulse Pressure mmHg ± SD | ||||
| Baseline | 65 ± 20 | 72 ± 12 | 64 ± 20 | 0.26 |
| Post TAVR—Day 1 | 63 ± 20 | 70 ± 11 | 62.4 ± 21 | 0.3 |
| Post TAVR—Day 3 | 63 ± 20 | 69 ± 10 | 62 ± 21 | 0.3 |
| Resistive arterial load—dynes/s/cm—5 ± SD | ||||
| Baseline | 2905 ± 1217 | 2743 ± 1272 | 2923 ± 1217 | 0.66 |
| Post TAVR—Day 1 | 2755 ± 1506 | 3500 ± 3454 | 2672±1117 | 0.09 |
| Post TAVR—Day 3 | 2631 ± 1069 | 2512 ± 888 | 2644±1091 | 0.71 |
| Systolic Blood Pressure—mmHg ± SD | ||||
| Baseline | 135 ± 22 | 143 ± 22 | 134 ± 22 | 0.21 |
| Post TAVR—Day 1 | 132 ± 22 | 129 ± 22 | 132 ± 22 | 0.66 |
| Post TAVR—Day 3 | 127 ± 25 | 133 ± 18 | 126 ± 25 | 0.42 |
| Diastolic Blood Pressure—mmHg ± SD | ||||
| Baseline | 70 ± 12 | 71 ± 17 | 70 ± 12 | 0.7 |
| Post TAVR—Day 1 | 65 ± 13 | 63 ± 9 | 65 ± 13 | 0.69 |
| Post TAVR—Day 3 | 64 ± 9 | 64 ± 10 | 64 ± 10 | 0.93 |
| Mean Arterial Pressure—mmHg ± SD | ||||
| Baseline | 91 ± 13 | 97 ± 16 | 90 ± 13 | 0.97 |
| Post TAVR—Day 1 | 88 ± 13 | 86 ± 12 | 88 ± 13 | 0.59 |
| Post TAVR—Day 3 | 86 ± 13 | 91 ± 17 | 85 ± 13 | 0.19 |
Data are presented as mean ± or n (%). AKI = acute kidney injury; TAVR = Transcatheter aortic valve replacement.