Table 4.
Best quality of life response: overall data (A) and gender stratification (B).
| Overall Response | Gender Stratification | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SCALE/ITEM | RESULT TREND ^ | |||||||||||
| Improved | Stable | Worsened | Improved | Stable | Worsened | |||||||
| n | (%) | n | (%) | n | (%) | M n (%) |
F n (%) |
M n (%) |
F n (%) |
M n (%) |
F n (%) |
|
| EORTC | ||||||||||||
| Global health status | 55 | (55) | 27 | (27) | 18 | (18) | 28 (47) | 27 (68) | 17 (28) | 10 (25) | 15 (25) | 3 (7) |
| Physical function. | 39 | (39) | 26 | (26) | 35 | (35) | 22 (37) | 17 (43) | 16 (26) | 10 (25) | 22 (37) | 13 (32) |
| Emotional function. | 54 | (54) | 27 | (27) | 19 | (19) | 31 (52) | 23 (58) | 17 (28) | 10 (25) | 12 (20) | 7 (17) |
| Fatigue | 53 | (53) | 19 | (19) | 28 | (28) | 30 (50) | 23 (58) | 13 (22) | 6 (15) | 17 (28) | 11 (27) |
| Nausea/vomiting | 27 | (27) | 59 | (59) | 14 | (14) | 17 (28) | 10 (25) | 34 (57) | 25 (63) | 9 (15) | 5 (12) |
| Pain | 61 | (61) | 28 | (28) | 11 | (11) | 31 (52) | 30 (75) | 21 (35) | 7 (18) | 8 (13) | 3 (7) |
| Dyspnea | 29 | (29) | 60 | (60) | 11 | (11) | 23 (38) | 6 (15) | 32 (54) | 28 (70) | 5 (8) | 6 (15) |
| Sleep disturbance | 45 | (45) | 40 | (40) | 15 | (15) | 27 (45) | 18 (45) | 23 (38) | 17 (43) | 10 (17) | 5 (12) |
| Appetite loss | 38 | (38) | 42 | (42) | 20 | (20) | 20 (33) | 18 (45) | 26 (44) | 16 (40) | 14 (23) | 6 (15) |
| Constipation | 36 | (36) | 45 | (45) | 19 | (19) | 22 (37) | 14 (35) | 24 (40) | 21 (53) | 14 (23) | 5 (12) |
| PSQI Sleep disorders | 39 | (40) | 42 | (43) | 16 | (17) | 20 (34) | 19 (50) | 29 (49) | 13 (34) | 10 (17) | 6 (16) |
| ESAS | 62 | (63) | 6 | (6) | 31 | (31) | 37 (62) | 25 (64) | 4 (6) | 2 (5) | 19 (32) | 12 (31) |
Notes: ^ Improved=score ≥10 points were better than baseline anytime; worsened = score ≥10 points lower than baseline without having improved at any time; stable = score changes ≤ 10 points from baseline. Abbreviations: EORTC QLQ-C15-PAL, European Organization of Research and Treatment Quality of Life Questionnaire-Cancer 15; PSQI, Pittsburgh Sleep Quality Index; ESAS, Edmonton Symptom Assessment System.