Table 2.
Overview of all the DMGs found in this study alongside the relevant statistics. In short, p-values were obtained using Brown’s method and adjusted for multiple testing using the Benjamini–Hochberg method against all genes.
| CD vs. Non-CD | CD-Active vs. CD-Remissive | |||
|---|---|---|---|---|
| Differentially Methylated Gene | p-Value | BH-Adjusted p-Value | p-Value | BH-Adjusted p-Value |
| MPIG6B (C6orf25) | 4.63 × 10−15 | 9.19 × 10−11 | 1.08 × 10−9 | 2.15 × 10−5 |
| PDCD1 | 4.05 × 10−10 | 8.04 × 10−6 | 0.905923 | 1 |
| GSTT1 | 3.60 × 10−9 | 7.16 × 10−5 | 0.317294 | 1 |
| ZADH2 | 4.54 × 10−9 | 9.02 × 10−5 | 0.028386 | 1 |
| MS4A3 | 6.90 × 10−9 | 0.000136924 | 0.873469 | 1 |
| DRD4 | 3.15 × 10−8 | 0.000625727 | 0.283934 | 1 |
| SLFN13 | 3.27 × 10−8 | 0.000649811 | 0.010163 | 1 |
| SLC17A9 | 1.67 × 10−7 | 0.003305914 | 0.14758 | 1 |
| MPEG1 | 2.00 × 10−7 | 0.003965532 | 0.498594 | 1 |
| SLC26A4 | 2.66 × 10−7 | 0.005275024 | 0.612185 | 1 |
| SPI1 | 5.95 × 10−7 | 0.011817048 | 0.007133 | 1 |
| LOC286002 | 8.54 × 10−7 | 0.016951922 | 0.578701 | 1 |
| ZNF572 | 1.09 × 10−6 | 0.02165659 | 0.3022 | 1 |
| LOC150381 | 1.72 × 10−6 | 0.034101222 | 0.935613 | 1 |
| G0S2 | 1.74 × 10−6 | 0.03460972 | 0.560081 | 1 |
| NNAT | 1.88 × 10−5 | 0.372484 | 2.98 × 10−12 | 5.91 × 10−8 |
| SERPINF1 | 0.204451 | 1 | 1.13 × 10−10 | 2.24 × 10−6 |
| TRIOBP | 0.634584 | 1 | 9.00 × 10−9 | 1.79 × 10−4 |
| KRTCAP3 | 0.992178 | 1 | 1.31 × 10−8 | 2.61 × 10−4 |
| TRIP6 | 0.036528 | 1 | 3.64 × 10−8 | 7.22 × 10−4 |
| LOC387647 | 0.998103 | 1 | 5.43 × 10−8 | 1.08 × 10−3 |
| HCP5 | 0.809063 | 1 | 7.04 × 10−8 | 1.40 × 10−3 |
| SSTR4 | 0.873458 | 1 | 2.34 × 10−7 | 4.64 × 10−3 |
| FAM24B | 0.071767 | 1 | 9.33 × 10−7 | 0.018513 |
| ZNF154 | 0.003772 | 1 | 2.16 × 10−6 | 0.042834 |
| PRAP1 | 0.901922 | 1 | 2.24 × 10−6 | 0.044415 |