Table 3.
Age Group | ||||
---|---|---|---|---|
Medication Class, N (%) | Total (N = 4447) |
50–64 Years (N = 2662) |
65–74 Years (N = 1238) |
75+ Years (N = 547) |
Number of medications per patient, mean (SD), IQR | 2.4 (2.54) 3 (0–4) |
2.4 (2.52) 3 (0–4) |
2.4 (2.57) 3 (0–4) |
2.3 (2.58) 3 (0–4) |
Antidepressants | 1060 (23.8) | 670 (25.2) | 289 (23.4) | 101 (18.5) |
Antipsychotics | 128 (2.9) | 82 (3.1) | 35 (2.8) | 11 (2.0) |
Anxiolytics and benzodiazepines | 1046 (23.5) | 674 (25.3) | 285 (23.0) | 87 (15.9) |
Mood stabilizers | 37 (0.8) | *** | *** | *** |
Stimulants and amphetamines | 124 (2.8) | *** | *** | *** |
Hypnotics and sedatives | 292 (6.6) | 168 (6.3) | 98 (7.9) | 26 (4.8) |
Opioids ± | 1271 (28.6) | 863 (32.4) | 296 (23.9) | 112 (20.5) |
Non-opioid analgesics | 861 (19.4) | 512 (19.2) | 229 (18.5) | 120 (21.9) |
Skeletal muscle relaxants | 611 (13.7) | 458 (17.2) | 127 (10.3) | 26 (4.8) |
Other musculoskeletal agents †† | 133 (3.0) | 73 (2.7) | 38 (3.1) | 22 (4.0) |
Anticonvulsants and antiepileptics | 760 (17.1) | 496 (18.6) | 176 (14.2) | 88 (16.1) |
Anti-Parkinson | 162 (3.6) | 58 (2.2) | 69 (5.6) | 35 (6.4) |
Other neurological agents ±± | 71 (1.6) | 39 (1.5) | 21 (1.7) | 11 (2.0) |
Antiemetics | 200 (4.5) | 128 (4.8) | 56 (4.5) | 16 (2.9) |
Other GI agents | 217 (4.9) | 135 (5.1) | 58 (4.7) | 24 (4.4) |
Cardiovascular agents | 1241 (27.9) | 623 (23.4) | 417 (33.7) | 201 (36.8) |
Antidiabetic agents | 271 (6.1) | 147 (5.5) | 92 (7.4) | 32 (5.9) |
Hematologic agents | 126 (2.8) | 52 (2.0) | 51 (4.1) | 23 (4.2) |
Hormonal agents and steroids | 596 (13.4) | 319 (12.0) | 198 (16.0) | 79 (14.4) |
Genitourinary agents | 264 (5.9) | 99 (3.7) | 100 (8.1) | 65 (11.9) |
Respiratory agents | 181 (4.1) | 90 (3.4) | 60 (4.9) | 31 (5.7) |
Chemotherapeutic agents | 102 (2.3) | *** | *** | *** |
Autoimmune agents | 75 (1.7) | *** | *** | *** |
Antivirals incl. HIV medications | 40 (0.9) | *** | *** | *** |
Anti-infective agents | 50 (1.1) | *** | *** | *** |
Ophthalmic and glaucoma medications | 51 (1.2) | 17 (0.6) | 18 (1.5) | 16 (2.9) |
OTC medications, vitamins, supplements and others | 348 (8.2) | 204 (7.6) | 111 (9.0) | 48 (8.8) |
SD = standard deviation; IQR = interquartile range. † Medications are not mutually exclusive, more than one medication per patient possible. ± Includes combination products containing an opioid; †† Includes medications for multiple sclerosis. ±± Includes triptans and medications for Alzheimer’s disease. *** Data suppressed due to low cell count < 11.