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. 2020 Mar 30;12(4):956. doi: 10.3390/nu12040956

Figure 2.

Figure 2

Histological evaluation of joints activity after administration with FlexPro MD® (FP-MD) in monosodium iodoacetate (MIA)-induced osteoarthritis (OA) rats. (A) Knee joints of the OA rats were stained with hematoxylin and eosin (H&E) and Safranin O-Fast green. (B) The joint lesions were graded on a scale of 0–13 using the modified Mankin’s scoring system, giving a combined score for cartilage structure. Data are expressed as the mean ± S.E.M (n = 8). # p < 0.05 versus vehicle-treated Sham group and * p < 0.05 versus MIA. CLX; celecoxib 3 mg/kg-treated.