Table 1.
Characteristics of studied patients with primary and secondary hypogammaglobulinemia.
| Primary Hypogammaglobulinemia (1) | Secondary Hypogammaglobulinemia (2) | p - Value | |
|---|---|---|---|
| Number (n) | 38 | 38 | |
| Male Gender (n (%)) | 13 (34.21) | 10 (26.32) | ns |
| Current Age (Mean (IQR)) | 51.82 y (37.5–60) | 57.66 y (52–66.25) | ns |
| Age at Diagnosis of Hypogammaglobulinemia (Mean (IQR)) | 38.5 y (24.75–53.75) | 53.42 y (47.5–61.25) | *** (<0.0001) |
| Patients Treated with Immunoglobulin Replacement (n (%)) | 37 (97.37) | 7 (18.42) | *** (<0.0001) |
| IgG (Mean (IQR)) | 2.74 g/L (0.71–4.6) | 5.63 g/L (4.99–6.22) | *** (<0.0001) |
| IgA (Mean (IQR)) | 0.45 g/L (0.04–0.48) | 1.45 g/L (0.77–1.97) | *** (<0.0001) |
| IgM (Mean (IQR)) | 0.69 g/L (0.18–0.96) | 0.83 g/L (0.52–1.05) | *** (0.0003) |
| Absolute Lymphocyte Count (Mean (IQR)) | 1653 (1019–2080) | 1469 (1011–1838) | ns |
| Lymphocyte Percentage (Mean (IQR)) | 22.82 (16.75–28.25) | 20.92 (13–27) | ns |
IQR, interquartile range; ns, non-significant; y, years.