Table A1.
Univariate and multivariate analysis for in-hospital mortality.
| Survivors, Median (IQR), mg/dL | Non-Survivors, Median (IQR), mg/dL | p | Univariate Regression, OR (95%CI) | p | Multivariate Regression C. OR (95%CI) | p | AUC | |
|---|---|---|---|---|---|---|---|---|
| n | 161 | 129 | 290 | 290 | 290 | |||
| SM C16:0 | 104 (82, 143) | 111 (85.90, 136) | 0.64 | 0.95 (0.26, 3.55) | 0.94 | 1.30 (0.28, 5.97) | 0.74 | 0.52 |
| SM C16:1 | 14.60 (11.30, 20.00) | 15.70 (11.20, 19.40) | 0.92 | 0.86 (0.23, 3.18) | 0.82 | 1.00 (0.21, 4.75) | 1.00 | 0.50 |
| SM C18:0 | 21.20 (16.90, 30.30) | 21.70 (15.20, 29.30) | 0.63 | 0.58 (0.18, 1.93) | 0.38 | 0.86 (0.22, 3.47) | 0.84 | 0.52 |
| SM C18:1 | 10.10 (7.40, 13.00) | 9.87 (7.01, 12.90) | 0.59 | 0.60 (0.19, 1.94) | 0.40 | 0.80 (0.20, 3.22) | 0.76 | 0.52 |
| SM C20:2 | 0.58 (0.35, 0.89) | 0.61 (0.38, 0.85) | 0.45 | 1.38 (0.52, 3.66) | 0.51 | 1.43 (0.46, 4.50) | 0.54 | 0.52 |
| SM C22:3 | 3.24 (2.35, 5.18) | 3.24 (2.06, 4.50) | 0.22 | 0.49 (0.20, 1.24) | 0.13 | 0.75 (0.26, 2.17) | 0.60 | 0.55 |
| SM C24:0 | 14.30 (10.20, 19.40) | 12.80 (9.40, 16.60) | 0.07 | 0.30 (0.10, 0.97) | 0.05 | 0.48 (0.12, 1.88) | 0.29 | 0.56 |
| SM C24:1 | 35.10 (28.60, 46.20) | 36.20 (27.80, 44.40) | 0.79 | 0.67 (0.19, 2.37) | 0.54 | 0.87 (0.20, 3.76) | 0.86 | 0.51 |
| SM C26:0 | 0.15 (0.12, 0.21) | 0.16 (0.11, 0.23) | 0.83 | 0.95 (0.37, 2.40) | 0.91 | 1.25 (0.42, 3.69) | 0.69 | 0.51 |
| SM C26:1 | 0.28 (0.21, 0.37) | 0.28 (0.21, 0.36) | 0.45 | 0.50 (0.16, 1.53) | 0.23 | 0.58 (0.15, 2.26) | 0.44 | 0.53 |
| SM (OH) C14:1 | 6.46 (4.80, 8.66) | 6.88 (4.60, 9.07) | 0.75 | 1.08 (0.35, 3.28) | 0.89 | 0.97 (0.26, 3.62) | 0.97 | 0.51 |
| SM (OH) C16:1 | 3.4 (2.6, 4.57) | 3.62 (2.23, 5.05) | 0.84 | 0.73 (0.25, 2.17) | 0.57 | 0.75 (0.21, 2.68) | 0.66 | 0.51 |
| SM (OH) C22:1 | 9.33 (6.90, 12.60) | 8.19 (6.07, 11.50) | 0.04 | 0.28 (0.09, 0.88) | 0.03 | 0.34 (0.09, 1.28) | 0.11 | 0.57 |
| SM (OH) C22:2 | 8.18 (5.97, 10.70) | 7.81 (5.91, 9.95) | 0.33 | 0.49 (0.15, 1.59) | 0.24 | 0.43 (0.11, 1.71) | 0.23 | 0.53 |
| SM (OH) C24:1 | 1.05 (.80, 1.33) | 0.95 (0.71, 1.29) | 0.05 | 0.28 (0.08, 0.96) | 0.04 | 0.30 (0.07, 1.30) | 0.11 | 0.57 |
| Total sum of SM | 233.20 (183.00, 309.50) | 241.10 (182.60, 300.60) | 0.90 | 0.67 (0.17, 2.54) | 0.55 | 0.93 (0.20, 4.41) | 0.93 | 0.50 |
Data are presented as number (n) and percentage (%) or median (interquartile range) or odds ratio (OR) and 95% confidence interval (CI). SM: Sphingomyelin; Multivariate regression C: adjusted for age, gender and clinical shock markers. AUC: Area under the curve.