Table 3.
Hazard ratios (HR) and 95% confidence intervals (CI) of the association between initial misdiagnosis, sex, smoking, age at MS onset, BMI, age of the patients, and DMT and reaching EDSS 6.
| Predictors of Reaching the Milestone | HR | CI (95%) | p |
|---|---|---|---|
| Misdiagnosis | |||
| - Not misdiagnosed (N = 75) | - | - | 1 |
| - Misdiagnosed (N = 53) | 0.55 | 0.24–1.3 | 0.17 |
| Sex | |||
| - Female (N = 84) | - | - | 1 |
| - Male (N = 44) | 0.87 | 0.35–2.2 | 0.77 |
| History of smoking | |||
| - No (N = 106) | - | - | 1 |
| - Yes (N = 22) | 1.15 | 0.39–3.3 | 0.8 |
| Age at MS onset | |||
| - <18 (N = 9) | 0.61 | 0.07–4.9 | 0.64 |
| - 18–50 (N = 114) | - | - | 1 |
| - >50 (N = 5) | 2.49 | 0.39–15.8 | 0.33 |
| BMI | |||
| - <18.5 (N = 8) | 1.92 | 0.53–6.9 | 0.318 |
| - 18.5–24.9 (N = 88) | - | - | 1 |
| - 25–29.9 (N = 22) | 2.2 | 0.82–5.9 | 0.12 |
| - ≥30 (N = 10) | 1.04 | 0.22–4.9 | 0.96 |
| Age | |||
| - 18–50 (N = 107) | - | - | 1 |
| - >50 | 1.34 | 0.49–3.7 | 0.57 |
| DMT | |||
| - Did not receive DMT (N = 70) | - | - | 1 |
| - Received DMT (N = 58) | 0.66 | 0.3–1.4 | 0.29 |