(A) Insulin concentrations obtained during oral glucose tolerance tests (oGTT) in Wistar rats submitted to IF for 12 weeks. (B) Content-corrected insulin secretion, (C) insulin secretion, and (D) insulin content values in pancreatic islets isolated from Wistar rats submitted to IF for 12 weeks, after one hour of incubation in the presence of 2.8, 5.6, 8.3, 11.1, and 16.7 mM glucose. The results are presented as the means ± standard error of the mean (SEM) with 5 different animals for each group. * p <0.05 and ** p <0.005 compared to the control at the same time, as indicated by two-way ANOVA followed by Sidak’s multiple comparisons test.