Figure 5.

Effects of dietary supplementation on glial activation. (A) Representative Western blots from retinal homogenates of control mice or mice that received MCE fed with either vehicle or diet supplement. (B,C) Densitometric analysis of ionized calcium binding adaptor molecule 1 (Iba1; (B)) or glial fibrillary acidic protein (GFAP; C) levels. MCE resulted in increased levels of both Iba1 and GFAP. Dietary supplementation prevented the upregulation of Iba1 and GFAP (n = 6 for each group). * p < 0.001 versus control; ^§ p < 0.001 versus MCE mice fed with vehicle (one-way ANOVA followed by the Newman–Keuls multiple comparison post-hoc test).