Figure 7.

Effects of dietary supplementation on apoptotic markers. (A) Representative Western blots from retinal homogenates of control mice or mice that received MCE fed with either vehicle or diet supplement. (B,C) Densitometric analysis of the levels of Bax/Bcl-2 (B) and active caspase 3 (C). MCE resulted in increased levels of both Bax and active caspase 3 without altering Bcl-2 levels. Dietary supplementation prevented the upregulation of both Bax and the active form of caspase 3 (n = 6 for each group). * p < 0.05, ** p < 0.01 and *** p < 0.001 versus control; ^§ p < 0.001 versus MCE mice fed with vehicle (one-way ANOVA followed by the Newman–Keuls multiple comparison post-hoc test).