Table 1.
Group | Surgery/Sampling Time | Bloods | Total Blood Volumes (mL) | n | F:M | Median Age (Range) |
---|---|---|---|---|---|---|
Reaming | Patients undergoing reaming | FV+PV | 510 + 510 | 24 | 10:14 | 44.5 (18–66) |
a) Sequential conventional reaming for IM nailing of closed tibial shaft fracture. | FV+PV | 360 + 360 | 9 | 3:6 | 40 (18–53) | |
b) All fracture non-union patients requiring RIA for bone graft acquisition. | FV+PV | 150 + 150 | 15 | 7:8 | 45 (19–66) | |
Prior surgery | Current surgery not relevant #, samples taken before surgical intervention | FV+PV | 120 + 120 | 12 | 5:7 | 40 (18–67) |
Early RA | N/A | PV | 168 | 15 | 11:4 | 51 (23–77) |
Established RA | N/A | PV | 168 | 11 | 7:4 | 47 (32–66) |
HC | N/A | PV | 120 | 12 | 4:8 | 33.5 (24–54) |
OVERALL | FV + PV | 630 + 1086 | 74 | 37:37 | 43.5 (18–77) |
F = female, M = male, FV = femoral vein, PV = peripheral vein, RA = rheumatoid arthritis, HC = healthy control, IM = intramedullary, RIA = reamer/irrigator/aspirator. # available in Supplementary Table S1.