Table 2.
Differences between blood-MSCs and FVB-MSCs, and other MSC types.
| ICBM-MSCs | LBM-MSCs | CB-MSCs | Peri-MSCs | A-MSCs | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Comparator | BL-MSCs | FVB- MSCs | BL-MSCs | FVB- MSCs | BL-MSCs | FVB- MSCs | BL-MSCs | FVB- MSCs | BL-MSCs | FVB-MSCs |
| ACTA2 | 0.028 | |||||||||
| ACVR1B | 0.005 | 0.009 | ||||||||
| ACVR2A | 0.010 | 0.032 | <0.001 | 0.002 | ||||||
| BGLAP | 0.006 | 0.008 | 0.010 | 0.014 | ||||||
| BMP2 | 0.012 | 0.042 | ||||||||
| CEBPA | 0.027 | <0.001 | 0.002 | 0.018 | 0.001 | 0.004 | ||||
| COL1A2 | 0.021 | |||||||||
| CXCL12 | 0.013 | |||||||||
| DAAM2 | 0.016 | |||||||||
| DVL2 | 0.041 | 0.003 | 0.011 | |||||||
| EFNA1 | 0.040 | |||||||||
| FABP4 | 0.029 | 0.008 | 0.038 | 0.008 | 0.020 | |||||
| FZD9 | 0.038 | 0.008 | ||||||||
| GJA1 | 0.037 | 0.042 | ||||||||
| IGF2 | 0.048 | |||||||||
| MCAM | 0.038 | |||||||||
| MSX1 | 0.003 | 0.030 | 0.050 | |||||||
| NOG | 0.014 | |||||||||
| PPARG | 0.043 | 0.041 | ||||||||
| RUNX2 | 0.017 | |||||||||
| SORT1 | 0.006 | |||||||||
| SP7 | 0.008 | |||||||||
| SPP1 | 0.017 | 0.041 | <0.001 | 0.038 | ||||||
| TGFBR3 | 0.015 | <0.001 | 0.001 | |||||||
| Differences (BL-MSCs) | 8 | 9 | 9 | 5 | 8 | |||||
| ANGPTL4 | 0.012 | |||||||||
| BMPER | 0.021 | 0.031 | ||||||||
| DDR2 | 0.046 | <0.001 | ||||||||
| FGFR1 | 0.005 | |||||||||
| GHR | 0.012 | |||||||||
| PCOLCE | 0.027 | 0.005 | ||||||||
| S1PR1 | 0.033 | |||||||||
| TGFBR2 | 0.002 | 0.004 | ||||||||
| VEGFC | 0.012 | <0.000 | ||||||||
| Differences (FVB-MSCs) | 2 | 2 | 8 | 4 | 12 | |||||
Top 24 genes are different (p < 0.05) across all MSC types (Kruskal–Wallis) when all blood-MSCs (n = 6) are considered, the bottom 9 genes are only different (p > 0.05) when FVB-MSCs (n = 4) are considered independently. Multivariate p values < 0.05 are shown. BL = blood, IC = iliac crest, LB = long-bone, CB = control bone, peri = periosteum, A = adipose.