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. 2020 Apr 16;12(4):1108. doi: 10.3390/nu12041108

Table 5.

The microelement concentrations (in the 10–14th week of pregnancy) and pregnancy results.

Microelement Concentrations (µg/L) * (Mean ±SD)
SELENIUM
(Se)
IRON
(Fe)
ZINC
(Zn)
COPPER
(Cu)
Pregnancy Results n
Gestational age at birth
<34th week 17 56.71 (40.91) 904.82 (270.51) 599.35 (85.06) 1832.31 (393.00)
≥34th week 546 60.88 (41.14) 1021.87 (343.44) 619.09 (151.14) 1732.91 (318.39)
p-value ** 0.043 0.186 0.388 0.188
Gestational age at birth
<37th week 47 58.97 (8.20) 925.40 (232.10) 604.76 (75.82) 1751.74 (335.29)
≥37th week 516 60.91 (8.43) 1026.80 (349.09) 619.75 (154.52) 1734.47 (319.89)
p-value ** 0.148 0.091 0.561 0.556
Birth weight <10′
<10 percentile 48 59.60 (41.14) 969.28 (301.28) 631.09 (97.19) 1651.58 (268.92)
≥10 percentile 515 60.89 (40.91) 1022.90 (345.31) 617.32 (153.55) 1743.77 (324.46)
p-value ** 0.303 0.374 0.143 0.031
Birth weight >90′
>90 percentile 64 59.66 (45.17) 974.11 (295.33) 616.04 (84.85) 1731.86 (301.55)
≤90 percentile 499 60.86 (40.91) 1024.00 (347.23) 618.81 (156.00) 1736.43 (323.61)
p-value ** 0.296 0.361 0.903 0.853
IUGR
Yes 13 55.59 7.90 910.08 271.15 636.82 64.06 1577.29 336.24
No 550 60.87 8.40 1020.89 343.14 618.06 151.00 1739.66 319.93
p-value 0.026 0.316 0.159 0.113
Pregnancy-induced hypertension (PIH)
PIH cases 120 57.56 (40.91) 948.86 (333.73) 610.16 (87.95) 1699.48 (299.35)
Normotensive controls 443 61.62 (41.14) 1037.15 (341.97) 620.75 (162.28) 1745.78 (326.15)
p-value ** 0.000002 0.014 0.976 0.235
Gestational diabetes mellitus (GDM)
GDM cases 110 61.88 (44.39) 964.03 (313.88) 629.20 (104.66) 1798.27 356.53
Women without GDM 453 60.48 (40.91) 1031.52 (347.36) 615.90 (158.54) 1720.77 310.21
p-value ** 0.161 0.039 0.084 0.061

* Microelement concentrations were measured in serum samples from the 10–14th gestational week; ** p-value was obtained using the nonparametric Mann–Whitney U test (p < 0.05 was considered to be significant; IUGR: Intrauterine growth restriction; PIH: Pregnancy-induced hypertension (105 cases of gestational hypertension and 15 cases of preeclampsia); GDM: Gestational diabetes mellitus (90 cases of GDM-1 and 20 cases of GDM-2).