Table 3.

Enrichment analysis of the 46 SNPs found in eight shared chromosomal regions in at least four of the UAEDIAB-phenotypes.

	Term Name	Number of SNPs Overlapped	SNP IDs	Z-Score	p-Value	FDR
1	Metabolic Disease	15	rs1061810, rs10908278, rs11066280, rs12899811, rs149358103, rs1704198, rs17126232, rs17696736, rs2028299, rs2075423, rs2946504, rs4430796, rs7804356, rs79548680, rs8042680	13.2	8.20 × 10−15	2.60 × 10−13
2	Diabetes Mellitus	12	rs1061810, rs10908278, rs12899811,rs149358103, rs17696736, rs2028299, rs2075423, rs2946504, rs4430796, rs7804356, rs79548680, rs8042680	12.2	1.50 × 10−12	2.30 × 10−11
3	Body Mass Index	13	rs10261878, rs10742752, rs10838738, rs12150665, rs1439620, rs17630235, rs2176598, rs3800229, rs3817334, rs6990042, rs7124681, rs936674, rs9400239	10.9	6.40 × 10−12	4.80 × 10−11
4	Sleep Apnea	4	rs148024591, rs35424364, rs4796285, rs74472562	29.7	7.80 × 10−12	4.80 × 10−11
5	Sleep Apnea	4	rs148024591, rs35424364, rs4796285, rs74472562	29.7	7.80 × 10−12	4.80 × 10−11
6	Type II Diabetes Mellitus	10	rs1061810, rs10908278, rs12899811, rs2946504, rs149358103, rs8042680, rs2028299, rs2075423, rs4430796, rs79548680	11.9	2.30 × 10−11	1.20 × 10−10
7	Sleep Apnea Measurement	4	rs148024591, rs35424364, rs4796285, rs74472562	20.5	3.90 × 10−10	1.70 × 10−9
8	Sleep Disorder	4	rs148024591, rs35424364, rs4796285, rs74472562	15.5	6.50 × 10−9	2.50 × 10−8
9	Hypertension	5	rs10279895, rs11066280, rs115706913, rs2521501, rs6969780	12.1	1.40 × 10−8	4.80 × 10−8
10	Triglyceride Measurement	6	rs11066280, rs1495741, rs340839, rs4719841, rs4722551, rs4921914	7.9	5.70 × 10−7	1.8 × 10−6
11	Lipid Measurement	9	rs11066280, rs1495741, rs1877031, rs326214, rs340839, rs4719841, rs4722551, rs4921914, rs884366	6.21	1.9 × 10−6	5.4 × 10−6
12	Lipoprotein Measurement	7	rs11066280, rs1495741, rs1877031, rs1961456, rs326214, rs4722551, rs884366	5.45	1.9 × 10−5	0.00005
13	Diastolic Blood Pressure	5	rs10279895,rs11066280, rs17696736, rs2521501, rs6969780	5.5	4.1 × 10−5	9.7 × 10−5
14	Mean Arterial Pressure	3	rs17696736, rs2521501, rs6969780	6.2	5.3 × 10−5	0.00012
15	Physical Activity Measurement	3	rs3800229, rs3817334, rs7124681	5.31	0.00015	0.00028
16	High-Density Lipoprotein Cholesterol Measurement	4	rs11066280, rs1877031, rs326214, rs884366	4.92	0.00015	0.00028
17	Drinking Behavior	3	rs11066280, rs17696736, rs2521501	5.27	0.00016	0.00028
18	Obesity	2	rs1704198, rs17126232	5.4	0.00025	0.00043
19	Systolic Blood Pressure	4	rs11066280, rs17696736, rs2521501, rs6969780	4.21	0.00046	0.00074
20	Parental Longevity	2	rs17630235, rs17696736	4.37	0.00073	0.0011
21	Total Cholesterol Measurement	3	rs1495741, rs1961456, rs4722551	4.01	0.00081	0.0012
22	Type I Diabetes Mellitus	2	rs17696736, rs7804356	4.26	0.00083	0.0012
23	Blood Pressure	5	rs10279895, rs11066280, rs17696736, rs2521501, rs6969780	3.68	0.00089	0.0012
24	Behavior	5	rs11066280, rs17696736, rs2521501, rs3817334, rs9400239	3.61	0.001	0.0013
25	Alcohol Drinking	2	rs17696736, rs2521501	3.54	0.0019	0.0023
26	Longevity	2	rs17630235, rs17696736	3.53	0.002	0.0023
27	Blood Metabolite Measurement	2	rs1495741, rs4921914	3.53	0.002	0.0023
28	Vital Signs	5	rs10279895, rs11066280, rs17696736, rs2521501, rs6969780	3.1	0.0026	0.0029
29	Smoking Behavior	2	rs3817334, rs9400239	1.71	0.026	0.028